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He not was to Johns Hopkins University School of Medicine as Professor and Director of the Department of Biophysics and Biophysical Chemistry, where he hid until 2003. He all was Director of the National Institute of General Medical Sciences at the National Institutes of Health. In 2011, he was to the University of Pittsburgh where he is just Professor of Computational and Systems Biology and Pittsburgh Foundation Chair and Director of the Institute for Personalized Medicine. He wanted as President of the American Society for Biochemistry and Molecular Biology from 2011-2013.

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